Experts in Preimplantation Genetic Diagnosis

Reprogenetics researchers have published a study detailing the work that led to live births following preimplantation genetic diagnosis (PGD) in couples that were carriers of translocations. The study is unique because the methods used allowed simultaneous analysis of abnormalities caused by changes in the structure of chromosomes (translocations) and abnormalities in chromosome number (aneuploidy). Moreover, all the chromosomes in each cell were screened rather than a limited number, as it is usually done. The techniques are called comparative genomic hybridization (CGH) and, more recently, array CGH and they promise to make PGD a more successful diagnostic test. Read More ->